Allergan, Inc

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Allergan, Inc. was an American global pharmaceutical company focused on eye care, neurosciences, medical dermatology, medical aesthetics, breast enhancement, obesity intervention, and urologics. Allergan, Inc. was known for producing a wide range of products, including the cosmetic treatment Botox (Botulinum toxin), eye care products like Restasis for dry eye, and the LAP-BAND adjustable gastric banding system for weight loss. The company was headquartered in Irvine, California, and had a rich history of innovation and expansion in the pharmaceutical and biotechnology industries.

History[edit | edit source]

Allergan was originally founded in 1948 by Gavin S. Herbert as a small eye care company. Over the decades, it expanded its portfolio through research and development and a series of acquisitions. Notably, in 2015, Allergan merged with Actavis, a prominent pharmaceutical company, in a deal valued at approximately $70.5 billion. Following the merger, the combined entity chose to operate under the Allergan brand, leveraging its strong market presence in aesthetics and dermatology. However, in 2019, AbbVie announced its intention to acquire Allergan in a cash and stock deal valued at about $63 billion, aiming to diversify its product portfolio beyond its blockbuster drug, Humira.

Products and Services[edit | edit source]

Allergan, Inc. developed, manufactured, and marketed a broad array of pharmaceuticals in several areas. Key product areas included:

  • Eye Care: Allergan was a leader in eye care, producing treatments for conditions such as glaucoma, dry eye, and eye infections. Products like Restasis have been pivotal in treating dry eye syndrome.
  • Neurosciences: The company's neurosciences portfolio was highlighted by Botox, which, beyond its cosmetic applications, was used to treat various medical conditions, including chronic migraine, spasticity, and excessive sweating.
  • Medical Aesthetics: Allergan was renowned for its medical aesthetics products, including dermal fillers and breast implants, catering to a growing demand for cosmetic enhancements.
  • Obesity Intervention: The LAP-BAND system offered a surgical solution for weight loss, reflecting the company's involvement in obesity treatment solutions.
  • Urologics: Allergan also focused on treatments for urological conditions, contributing to the development of therapies for overactive bladder and other disorders.

Acquisitions and Mergers[edit | edit source]

Throughout its history, Allergan pursued growth through strategic acquisitions and mergers. These not only expanded its product lines but also its global footprint. The merger with Actavis and the subsequent acquisition by AbbVie were significant milestones that shaped the company's trajectory in the global pharmaceutical market.

Controversies[edit | edit source]

Like many pharmaceutical companies, Allergan faced its share of controversies, including legal challenges and criticism over drug pricing and patent practices. One notable strategy involved transferring patents to the Saint Regis Mohawk Tribe to avoid patent challenges, a move that sparked debate over pharmaceutical patent protections and indigenous sovereignty.

Conclusion[edit | edit source]

Allergan, Inc.'s journey from a small eye care business to a global pharmaceutical giant reflects the dynamic nature of the pharmaceutical industry. Its legacy is marked by innovation in medical aesthetics, eye care, and neurosciences, contributing significantly to advancements in healthcare and medicine.

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Contributors: Prab R. Tumpati, MD