Alpha-Linolenic acid

From WikiMD's Wellness Encyclopedia

Alpha-Linolenic acid (ALA) is an omega-3 fatty acid that is essential to human health. It is a type of polyunsaturated fat that the body cannot produce on its own, so it must be obtained from the diet. ALA is found in many plant-based foods, including flaxseeds, chia seeds, and walnuts.

Etymology[edit | edit source]

The term "alpha-linolenic" comes from the Greek word "linon," meaning flax, and the Latin word "oleum," meaning oil. This is because ALA was first identified in flaxseed oil.

Structure and Function[edit | edit source]

ALA is a carboxylic acid with an 18-carbon chain and three cis double bonds. The first double bond is located at the third carbon from the methyl end of the fatty acid chain. This is why it is classified as an omega-3 fatty acid.

The body can convert small amounts of ALA into eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are more active in the body and can contribute to heart health and brain function. However, the conversion process is not very efficient, so it is recommended to consume EPA and DHA directly from food or supplements.

Health Benefits[edit | edit source]

Research has shown that ALA may have several health benefits. It has been associated with a lower risk of cardiovascular disease by improving heart health and reducing inflammation. It may also help to lower blood pressure and cholesterol levels.

Some studies suggest that ALA may have potential benefits for mental health. It may help to reduce symptoms of depression and other mental health disorders. However, more research is needed in this area.

Dietary Sources[edit | edit source]

The best dietary sources of ALA are flaxseeds, chia seeds, and walnuts. It can also be found in hemp seeds, soybeans, and certain types of vegetable oils, such as canola and soybean oil.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD