Alpha-gal

Alpha-gal syndrome (AGS) is a type of food allergy to certain types of meat. AGS has been linked to the Lone Star tick and some other species of ticks. The condition is named after the sugar molecule present in the meat, called galactose-alpha-1,3-galactose, or alpha-gal for short.

Symptoms

The symptoms of alpha-gal syndrome can vary from person to person. They can range from mild to severe and can include:

• Hives or skin rash
• Nausea, diarrhea, stomach cramps, or vomiting
• Headache
• Asthma
• Anaphylaxis, a severe, potentially life-threatening allergic reaction

Causes

Alpha-gal syndrome is thought to be caused by a reaction to a sugar molecule found in most mammals (except for humans and a few other primates). This molecule, called alpha-gal, is found in high levels in the meat of these animals. The body's immune system can react to this molecule, causing an allergic reaction.

Diagnosis

Diagnosis of alpha-gal syndrome is typically based on a combination of a person's medical history, symptoms, and the results of blood tests. The blood tests look for specific antibodies that the body produces in response to alpha-gal.

Treatment

There is currently no cure for alpha-gal syndrome. Treatment typically involves avoiding foods that contain alpha-gal. In some cases, medications may be used to manage symptoms.

See also

• Food allergy
• Tick

References

Alpha-gal Resources
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