Alzheimer's Disease Neuroimaging Initiative
Alzheimer's Disease Neuroimaging Initiative
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a major research project aimed at understanding the progression of Alzheimer's disease through the use of neuroimaging and other biomarkers. The initiative seeks to develop clinical, imaging, genetic, and biochemical biomarkers for the early detection and tracking of Alzheimer's disease.
History[edit | edit source]
The Alzheimer's Disease Neuroimaging Initiative was launched in 2004 as a public-private partnership, funded by the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), along with other federal agencies and private sector organizations. The project was designed to last for five years initially, but due to its success, it has been extended multiple times.
Objectives[edit | edit source]
The primary objectives of ADNI are to:
- Identify the best markers for early detection of Alzheimer's disease.
- Track the progression of Alzheimer's disease over time.
- Develop new diagnostic criteria and tools for Alzheimer's disease.
- Facilitate the development of new treatments by providing a large, publicly accessible database of imaging and biomarker data.
Methodology[edit | edit source]
ADNI employs a variety of neuroimaging techniques, including magnetic resonance imaging (MRI) and positron emission tomography (PET), to study changes in the brain associated with Alzheimer's disease. In addition to imaging, the initiative collects genetic data, cerebrospinal fluid (CSF) samples, and other biomarkers from participants.
Participant Recruitment[edit | edit source]
Participants in ADNI include individuals with normal cognition, mild cognitive impairment (MCI), and Alzheimer's disease. The study follows these participants over time to observe changes in their cognitive status and biomarkers.
Data Collection and Analysis[edit | edit source]
Data collected by ADNI is made available to researchers worldwide, allowing for extensive analysis and collaboration. The initiative has contributed to numerous scientific publications and has significantly advanced the understanding of Alzheimer's disease.
Impact[edit | edit source]
ADNI has had a profound impact on Alzheimer's research by providing a comprehensive dataset that has been used to:
- Validate biomarkers for Alzheimer's disease.
- Improve diagnostic criteria for early detection.
- Support the development of new therapeutic approaches.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
