Amiphenazole

Amiphenazole is a stimulant that is used in the treatment of hypotension, particularly in cases where the low blood pressure is caused by anesthesia. It is also used to treat respiratory depression caused by drug overdose or anesthesia.

Pharmacology

Amiphenazole works by stimulating the respiratory center of the brain, increasing the rate and depth of breathing. It also stimulates the vasomotor center, which results in vasoconstriction and an increase in blood pressure.

Medical Uses

Amiphenazole is primarily used in the treatment of hypotension and respiratory depression. It is particularly useful in cases where these conditions are caused by anesthesia or drug overdose.

Side Effects

Common side effects of Amiphenazole include nausea, vomiting, and restlessness. In rare cases, it can cause hypertension, tachycardia, and arrhythmia.

Contraindications

Amiphenazole is contraindicated in patients with hypertension, hyperthyroidism, and cardiac arrhythmia. It should also be used with caution in patients with coronary artery disease or diabetes.

History

Amiphenazole was first synthesized in the 1950s and has been used in medical practice since the 1960s.

See Also

• Stimulant
• Hypotension
• Respiratory depression
• Anesthesia