Amnios

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Amnios cover art

Amnios refers to the amniotic sac, a thin but durable sac or membrane filled with amniotic fluid that surrounds an embryo or fetus during pregnancy in amniotes, which include most mammals, reptiles, and birds. The amnios plays a critical role in the development of the fetus, providing a protective environment that cushions against mechanical shocks, maintains a stable temperature, and facilitates the exchange of water, nutrients, and biochemical products between the mother and the fetus.

Structure and Function[edit | edit source]

The amnios is composed of two layers: an inner layer called the amnion and an outer layer known as the chorion. The space between these layers is filled with amniotic fluid. This fluid is initially formed from the mother's plasma, and as the fetus grows, it contributes to the fluid by excreting urine into the amnios.

Amniotic fluid serves several functions:

  • It allows the fetus to move freely within the womb, which is important for muscle development and bone growth.
  • It acts as a cushion, protecting the fetus from external pressures and potential injuries.
  • It helps to regulate the temperature around the fetus, keeping it consistent.
  • It prevents the amniotic sac from adhering to the developing fetus, which can cause malformations or growth restrictions.

Clinical Significance[edit | edit source]

The amnios and amniotic fluid are subject to various clinical assessments during pregnancy to ensure the health and development of the fetus. These include:

  • Amniocentesis: A procedure where a small amount of amniotic fluid is extracted from the amnios for genetic testing, detection of congenital disorders, and assessment of fetal lung maturity.
  • Ultrasound: Used to visualize the amnios and monitor the amount of amniotic fluid, which can indicate the health of the fetus. Abnormal levels of amniotic fluid, such as oligohydramnios (too little fluid) or polyhydramnios (too much fluid), can be signs of potential complications.

Evolutionary Significance[edit | edit source]

The evolution of the amnios is a significant event in the history of life on Earth, allowing the ancestors of modern amniotes to reproduce away from aquatic environments. This adaptation facilitated the colonization of terrestrial habitats by providing an "internal pond" in which the embryo could develop, free from the risk of desiccation.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD