Androstenetriol
Androstenetriol is a steroid and metabolite of the hormone dehydroepiandrosterone (DHEA). It is classified as an androgen, a type of hormone that controls the development and maintenance of male characteristics by binding to androgen receptors.
Chemical Structure and Synthesis[edit | edit source]
Androstenetriol has a chemical structure similar to other androgens, such as testosterone and dihydrotestosterone (DHT). It is synthesized in the body from DHEA through a series of enzymatic reactions involving the enzymes 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase.
Biological Activity[edit | edit source]
Androstenetriol exerts its effects in the body by binding to and activating androgen receptors. This binding triggers a series of cellular events that lead to the expression of specific genes involved in male sexual development and function. In addition to its androgenic activity, androstenetriol has also been found to have immunomodulatory effects. It has been shown to suppress the production of proinflammatory cytokines, which are involved in the body's immune response to injury or infection.
Clinical Significance[edit | edit source]
Due to its immunomodulatory properties, androstenetriol has been investigated for potential therapeutic applications in conditions characterized by excessive inflammation, such as autoimmune diseases and chronic inflammatory diseases. However, more research is needed to fully understand its mechanisms of action and potential therapeutic benefits.
See Also[edit | edit source]
 | This article about a steroid is a stub. You can help WikiMD by expanding it. |
This hormone-related article is a stub. You can help WikiMD by expanding it.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
