Cyclothiazide
(Redirected from Anhydron)
Cyclothiazide is a diuretic and antihypertensive drug that belongs to the class of thiazide diuretics. It is primarily used in the treatment of hypertension and edema.
Mechanism of Action[edit | edit source]
Cyclothiazide works by inhibiting the sodium-chloride symporter in the distal convoluted tubule of the nephron. This results in an increase in the excretion of sodium, chloride, and water from the body, thereby reducing blood pressure and decreasing edema.
Side Effects[edit | edit source]
Common side effects of cyclothiazide include dizziness, headache, nausea, and vomiting. In rare cases, it can cause severe hypokalemia, hyponatremia, and hypercalcemia.
Contraindications[edit | edit source]
Cyclothiazide is contraindicated in patients with known hypersensitivity to thiazide diuretics or sulfonamide derivatives. It should also be used with caution in patients with severe renal impairment or hepatic impairment.
Interactions[edit | edit source]
Cyclothiazide can interact with several other medications, including digoxin, lithium, and nonsteroidal anti-inflammatory drugs (NSAIDs). It can also interact with alcohol, increasing the risk of orthostatic hypotension.
Dosage[edit | edit source]
The dosage of cyclothiazide varies depending on the condition being treated and the patient's response to therapy. It is usually taken once daily, either in the morning or evening.
See Also[edit | edit source]
Cyclothiazide Resources | |
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