Anistreplase

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Anistreplase is a plasminogen activator that is used as a thrombolytic agent to treat acute myocardial infarction (heart attack) and pulmonary embolism. It is a complex of human tissue plasminogen activator (t-PA) and streptokinase.

Mechanism of Action[edit | edit source]

Anistreplase works by converting plasminogen to plasmin, an enzyme that breaks down blood clots. This helps to restore blood flow in the blocked arteries and prevent damage to the heart muscle.

Uses[edit | edit source]

Anistreplase is used to treat acute myocardial infarction and pulmonary embolism. It is usually given as an intravenous injection.

Side Effects[edit | edit source]

The most common side effects of anistreplase include bleeding, allergic reactions, and low blood pressure. In rare cases, it can cause serious bleeding in the brain (intracranial hemorrhage).

Contraindications[edit | edit source]

Anistreplase should not be used in patients with a history of stroke, recent surgery, or active bleeding. It should also be avoided in patients with severe high blood pressure or a history of allergic reactions to streptokinase or t-PA.

Interactions[edit | edit source]

Anistreplase can interact with other medications, including anticoagulants, antiplatelet drugs, and certain blood pressure medications. It is important to tell your doctor about all the medications you are taking before starting treatment with anistreplase.

See Also[edit | edit source]


Anistreplase Resources

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