Arachidonic

From WikiMD's Food, Medicine & Wellness Encyclopedia

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6). It is structurally related to the saturated arachidic acid found in Cupuaçu butter.

Chemistry[edit | edit source]

Arachidonic acid is a polyunsaturated fatty acid present in the phospholipids (especially phosphatidylethanolamine, phosphatidylcholine, and phosphatidylinositides) of membranes of the body's cells, and is abundant in the brain, muscles, and liver.

Biosynthesis and cascade[edit | edit source]

In chemical structure, arachidonic acid is a carboxylic acid with a 20-carbon chain and four cis-double bonds; the first double bond is located at the sixth carbon from the omega end.

Role in the body[edit | edit source]

Arachidonic acid is one of the most abundant fatty acids in the brain, and is present in similar quantities to docosahexaenoic acid (DHA). The two account for approximately 20% of its fatty-acid content.

Dietary sources[edit | edit source]

Arachidonic acid is not one of the essential fatty acids. However, it does become essential if a deficiency in linoleic acid exists or if an inability to convert linoleic acid to arachidonic acid occurs.

See also[edit | edit source]

Arachidonic Resources
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Contributors: Prab R. Tumpati, MD