Band cell

Band cell A band cell (also called a band neutrophil, stab cell, or rod cell) is a cell type that arises during neutrophil maturation. These cells are a form of immature granulocyte, a type of white blood cell that plays a crucial role in the body's immune system. Band cells are characterized by their distinctive shape, which features a nucleus that is not yet fully segmented, instead appearing as a band or rod shape.

Morphology and Development

Band cells are an intermediate stage in the maturation of neutrophils, falling between metamyelocytes and mature neutrophils in the developmental sequence. The nucleus of a band cell is not yet fully segmented, instead appearing as a band or rod shape. This gives the cell its name. As the cell matures, the nucleus will become segmented, and the cell will become a mature neutrophil.

Clinical Significance

• An increased number of band cells in the blood, a condition known as bandemia, can be a sign of infection or inflammation. This is because the body produces more white blood cells to fight off infection, and some of these cells may be released into the bloodstream before they are fully mature. Bandemia is often seen in bacterial infections, but can also occur in other conditions such as trauma, pregnancy, or certain types of cancer.

• Conversely, a low number of band cells can indicate a problem with the bone marrow's ability to produce new cells, which can be seen in conditions such as aplastic anemia or certain types of leukemia.

See Also

• Neutrophil
• Granulocyte
• White blood cell
• Bandemia