Basic rest–activity cycle
Basic rest–activity cycle - brief summary
The basic rest–activity cycle (BRAC) is a physiological arousal mechanism in humans proposed by Nathaniel Kleitman, hypothesized to occur during both sleep and wakefulness. Empirically, it is an ultradian rhythm of approximately 90 minutes (80–120 minutes) characterized by different levels of excitement and rest. The cycle is mediated by the human biological clock. It is most readily observed in stages of sleep, for example, rapid eye movement sleep (REM) and the delta activity cycle.
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Contributors: Prab R. Tumpati, MD
