Batoclimab
Synonyms[edit source]
Batoclimab, BATOCLIMAB, HBM 9161, HBM-9161, HBM9161, HL 161, HL-161, HL161
Thesaurus
A human monoclonal antibody directed against the neonatal crystallizable fragment receptor (FcRn), with potential immunomodulating activity. Upon administration, batoclimab targets and binds to FcRn at the immunoglobulin G (IgG) binding site, thereby preventing the interaction between FcRn and the serum protein IgG. By preventing FcRn/IgG binding, batoclimab blocks the FcRn-mediated rescue of IgG, enables IgG degradation and prevents IgG-mediated inflammation. IgG plays a key role in many autoimmune diseases and is an important factor in inflammatory processes. Amino Acid, Peptide, or Protein, Pharmacologic Substance
- NCI Thesaurus (external)
C20401.
This concise article on Batoclimab incorporates public domain text from the US National Library of Medicine.
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