Benzilylcholine mustard

Benzilylcholine mustard (BCM) is a neurotoxin that is used in scientific research to induce neuronal degeneration. It is a derivative of benzylcholine, and acts by irreversibly binding to and inactivating the acetylcholine receptor.

Mechanism of action

BCM acts by binding irreversibly to the acetylcholine receptor, thereby inactivating it. This leads to a decrease in the number of functional acetylcholine receptors, which in turn leads to a decrease in the ability of the neuron to respond to acetylcholine. This can result in a variety of effects, including neuronal degeneration and muscle weakness.

Use in research

BCM is used in scientific research to study the effects of neuronal degeneration. It is often used in studies of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, as it can be used to induce a state similar to these diseases in laboratory animals.

Safety

As a neurotoxin, BCM is highly toxic and must be handled with care. It can cause severe health effects if ingested, inhaled, or absorbed through the skin. It is classified as a hazardous substance and must be handled and disposed of in accordance with local regulations.

See also

• Neurotoxin
• Acetylcholine receptor
• Neurodegenerative diseases

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