Beta-Endorphin

Beta-Endorphin is a peptide that is used by the body to inhibit the sensation of pain. It is one of the endorphins that are produced in the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.

Etymology

The term "Beta-Endorphin" comes from the words "endogenous" and "morphine", which means morphine produced naturally in the body. The "beta" designation is used because it is the second of five endorphins found in the pituitary gland.

Structure

Beta-Endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC). Beta-endorphin is found in neurons of the hypothalamus, as well as the pituitary gland.

Function

Beta-Endorphin has the ability to dull or block sensations of pain in the body. It does this by binding to and activating the opioid receptors in the brain, which block the release of neurotransmitters that signal pain. It is also involved in other physiological processes such as thermoregulation and appetite.

Related Terms

• Endorphins
• Pituitary gland
• Hypothalamus
• Opioid receptors
• Neurotransmitters

See Also

• Pain management
• Neuroscience
• Physiology

Beta-Endorphin Resources
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