Biermer's anemia

Biermer's Anemia also known as Pernicious Anemia is a type of anemia characterized by a decrease in red blood cells when the body can't absorb enough vitamin B12.

Causes

Biermer's Anemia is caused by a lack of intrinsic factor, a protein made in the stomach. This is needed to absorb vitamin B12 from food into the body. Without enough intrinsic factor, vitamin B12 can't be absorbed and is excreted in the feces. This leads to a decrease in red blood cells, causing anemia.

Symptoms

Symptoms of Biermer's Anemia include fatigue, weakness, pale skin, constipation, loss of appetite, weight loss, numbness or tingling in the hands and feet, balance problems, depression, confusion, dementia, and a sore mouth or tongue.

Diagnosis

Diagnosis of Biermer's Anemia involves blood tests to check the level of vitamin B12 in the blood, a complete blood count (CBC) to check the number and appearance of red blood cells, and a test to measure intrinsic factor antibodies.

Treatment

Treatment for Biermer's Anemia involves replacing the missing vitamin B12 in the body. This can be done through high-dose vitamin B12 pills, vitamin B12 shots, or nasal spray.

Prognosis

With treatment, people with Biermer's Anemia can manage their symptoms and live a normal life. However, if left untreated, the anemia can cause serious complications, including heart and nerve damage.

See Also

• Anemia
• Vitamin B12
• Intrinsic factor