Bleeding time
Bleeding Time[edit | edit source]
Introduction[edit | edit source]
Bleeding time is a clinical laboratory test primarily used to assess platelet function and the body's ability to form a clot and stop bleeding.
Test Overview[edit | edit source]
The bleeding time test measures the duration it takes for a superficial skin cut to cease bleeding. It evaluates platelet function and interaction with the vessel wall, providing insights into primary hemostasis.
Methodology[edit | edit source]
- Conventional Bleeding Time
In a conventional test, a small incision is made on the patient's skin, typically on the forearm. The time from the cut to the cessation of bleeding is measured.
- Template Bleeding Time
The term "template bleeding time" refers to a standardized version of the test. It involves using a template to make a precise incision depth and length, ensuring consistency in the test conditions.
Clinical Significance[edit | edit source]
Bleeding time is significant in diagnosing conditions related to platelet function, such as Von Willebrand disease and other coagulopathies. It helps in evaluating patients with a history of excessive bleeding.
Limitations and Considerations[edit | edit source]
The test has some limitations, including variability in results and a lack of sensitivity to mild platelet function disorders. It is also influenced by external factors like skin thickness and temperature.
Alternative Tests[edit | edit source]
Due to its limitations, bleeding time has been largely supplanted by other tests like platelet function analyzers (PFA) and coagulation tests.
Procedure and Safety[edit | edit source]
The procedure involves minimal risks, primarily localized bruising or infection at the incision site. It is crucial to maintain aseptic conditions during the test.
References[edit | edit source]
- Rodgers, R. P. C., & Levin, J. (1990). A critical reappraisal of the bleeding time. Seminars in Thrombosis and Hemostasis, 16(1), 1-20.
- Lippi, G., & Favaloro, E. J. (2011). Laboratory hemostasis: From biology to the bench. Clinica Chimica Acta, 412(1-2), 13-21.
See Also[edit | edit source]
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