Brefanolol

Brefanolol

Brefanolol is a beta blocker used in the treatment of hypertension and angina pectoris. It is a non-selective beta blocker that works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Pharmacology

Brefanolol is a beta-adrenergic antagonist, or beta blocker, which means it blocks beta receptors in the heart, blood vessels, and lungs. This blocking action can decrease the heart rate, reduce blood pressure, and alleviate symptoms of angina pectoris. Brefanolol is non-selective, meaning it blocks both beta-1 and beta-2 receptors.

Clinical Use

Brefanolol is primarily used in the treatment of hypertension and angina pectoris. It can also be used to prevent myocardial infarction (heart attack) in high-risk patients, and to manage symptoms of heart failure.

Side Effects

Like all medications, Brefanolol can cause side effects. Common side effects include fatigue, dizziness, and cold hands and feet. Less common side effects can include shortness of breath, uneven heartbeats, and swelling of the hands or feet.

Contraindications

Brefanolol is contraindicated in patients with severe bradycardia (slow heart rate), heart block, cardiogenic shock, and uncompensated heart failure. It should also be used with caution in patients with asthma or other respiratory conditions, as it can cause bronchospasm.

See Also

• Beta blocker
• Hypertension
• Angina pectoris
• Epinephrine
• Myocardial infarction
• Heart failure
• Bradycardia
• Heart block
• Cardiogenic shock
• Asthma