Brilliant green (dye)

Brilliant Green is a triarylmethane dye that belongs to the family of medicinal chemicals. It is also known as Malachite Green G, Solid Green JJO, and Ethyl Green. It is used as a topical antiseptic and has been used in the treatment of various infections.

Chemical Structure

Brilliant Green is a synthetic dye that consists of a central carbon atom connected to three aromatic rings. The chemical formula of Brilliant Green is C27H34N2O4S. It is a bright green powder that is soluble in water and alcohol.

Medical Uses

Brilliant Green is primarily used as a topical antiseptic. It is effective against gram-positive microorganisms, including Staphylococci and Streptococci. It is often used in combination with other antiseptics, such as proflavine and crystal violet, in a solution known as Gram's stain.

Pharmacology

When applied topically, Brilliant Green acts by disrupting the cell wall of microorganisms, leading to cell death. It is less effective against gram-negative bacteria due to their protective outer membrane. The exact mechanism of action is not fully understood, but it is believed to involve the inhibition of bacterial DNA synthesis.

Safety and Side Effects

Brilliant Green is generally safe for topical use. However, it can cause skin irritation and allergic reactions in some individuals. It should not be used on large wounds or severe burns due to the risk of systemic absorption and potential toxicity.

See Also

• Antiseptic
• Gram's Stain
• Malachite Green
• Proflavine
• Crystal Violet