Brodmann area 28

Region of the brain in the temporal lobe

Brodmann area 28 cytoarchitectonics

Brodmann area 28 (BA28) is a region of the cerebral cortex in the temporal lobe of the human brain. It is part of the parahippocampal gyrus and is involved in the processing of olfactory information and memory.

Anatomy

Brodmann area 28 is located in the medial temporal lobe, specifically within the parahippocampal gyrus. It is adjacent to Brodmann area 27 and Brodmann area 34. The area is characterized by its distinct cytoarchitecture, which differentiates it from surrounding cortical areas.

Function

BA28 is primarily associated with the processing of olfactory stimuli. It plays a crucial role in the perception and recognition of smells. Additionally, it is involved in memory formation and retrieval, particularly in the context of olfactory memories. The area is also implicated in the integration of sensory information with emotional responses.

Cytoarchitecture

Brodmann areas in the human brain

The cytoarchitecture of Brodmann area 28 is defined by its layered structure, which includes six distinct layers of neurons. These layers vary in cell density and type, contributing to the area's specific functional properties. The presence of large pyramidal cells in certain layers is notable, as these cells are involved in the transmission of information to other brain regions.

Clinical significance

Damage or dysfunction in Brodmann area 28 can lead to deficits in olfactory perception and memory. It may also be involved in certain neurological conditions, such as Alzheimer's disease, where olfactory dysfunction is an early symptom. Understanding the role of BA28 in these processes is important for developing therapeutic strategies.

Related pages

• Brodmann area 27
• Brodmann area 34
• Parahippocampal gyrus
• Olfactory system