Brodmann area 28

Brodmann area 28 is a region of the brain that is part of the cerebral cortex. It is also known as the entorhinal cortex and is located in the medial temporal lobe. This area plays a crucial role in memory and navigation.

Anatomy

Brodmann area 28 is located in the anterior part of the parahippocampal gyrus, which is situated on the medial surface of the temporal lobe. It is bordered by the perirhinal cortex (Brodmann area 35 and 36) posteriorly and the subiculum anteriorly.

File:Brodmann area 28.png

Brodmann area 28 in the human brain.

Function

The entorhinal cortex is a major input and output structure of the hippocampal formation. It plays a key role in declarative (or explicit) memory, which is the memory of facts and events. It is also involved in spatial navigation and is thought to contain a cognitive map of the environment.

Clinical significance

Damage to the entorhinal cortex can result in memory loss and disorientation. It is one of the first regions to be affected in Alzheimer's disease, which is characterized by memory loss and cognitive decline.

See also

• Brodmann area
• Cerebral cortex
• Entorhinal cortex
• Hippocampus
• Memory
• Navigation
• Alzheimer's disease

References

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