Brodmann area 6

Brodmann area 6 (BA6) is a region of the cerebral cortex in the human brain. It is part of the frontal lobe and is located just anterior to the primary motor cortex (Brodmann area 4). BA6 is involved in the planning of complex, coordinated movements and is divided into two main regions: the premotor cortex and the supplementary motor area (SMA).

Anatomy

Brodmann area 6 is situated in the frontal lobe of the brain, anterior to the central sulcus and Brodmann area 4. It extends from the superior frontal gyrus to the precentral gyrus. The region is cytoarchitectonically distinct from the surrounding areas, characterized by a lack of the internal granular layer (layer IV) and a prominent layer V.

Function

BA6 plays a crucial role in the planning and execution of voluntary movements. The premotor cortex, located in the lateral part of BA6, is involved in the preparation and initiation of movements, particularly those that are guided by external stimuli. The supplementary motor area, located medially, is involved in the coordination of movements that are internally generated, such as those requiring the use of both hands or the planning of complex sequences of movements.

Clinical Significance

Damage to Brodmann area 6 can result in motor deficits, such as apraxia, which is the inability to perform purposeful movements despite having the desire and physical capability to do so. Lesions in this area can also affect the ability to plan and execute complex motor tasks.

Research

Recent studies have shown that BA6 is involved in various cognitive functions beyond motor control, including working memory and attention. Functional imaging studies have demonstrated that BA6 is activated during tasks that require the integration of sensory information with motor planning.

See Also

• Brodmann area
• Frontal lobe
• Primary motor cortex
• Premotor cortex
• Supplementary motor area
• Apraxia