CADM1
CADM1 (Cell Adhesion Molecule 1) is a protein that in humans is encoded by the CADM1 gene. CADM1 is a member of the immunoglobulin superfamily and is involved in cell adhesion processes. It is also known as TSLC1 (Tumor Suppressor in Lung Cancer 1).
Function[edit | edit source]
CADM1 is a cell adhesion molecule involved in neuron-neuron adhesion, which may be essential for neuronal differentiation and maintenance. It also functions in the prevention of tumor metastasis.
Clinical significance[edit | edit source]
Mutations in the CADM1 gene are associated with various types of cancer, including lung cancer, breast cancer, and prostate cancer. CADM1 is considered a tumor suppressor gene, as its loss of function is associated with increased tumor growth and metastasis.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- CADM1 at the US National Library of Medicine Medical Subject Headings (MeSH)
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Contributors: Prab R. Tumpati, MD
