CADM1

CADM1 (Cell Adhesion Molecule 1) is a protein that in humans is encoded by the CADM1 gene. CADM1 is a member of the immunoglobulin superfamily and is involved in cell adhesion processes. It is also known as TSLC1 (Tumor Suppressor in Lung Cancer 1).

Function

CADM1 is a cell adhesion molecule involved in neuron-neuron adhesion, which may be essential for neuronal differentiation and maintenance. It also functions in the prevention of tumor metastasis.

Clinical significance

Mutations in the CADM1 gene are associated with various types of cancer, including lung cancer, breast cancer, and prostate cancer. CADM1 is considered a tumor suppressor gene, as its loss of function is associated with increased tumor growth and metastasis.

See also

• Cell adhesion
• Tumor suppressor gene
• Metastasis

External links

• CADM1 at the US National Library of Medicine Medical Subject Headings (MeSH)

CADM1 Resources
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