CPK-MB test
(Redirected from CKMB)
CPK-MB Test[edit | edit source]
The CPK-MB test is a blood test used to measure the level of the MB isoenzyme of Creatine kinase (CK) in the blood. This test is primarily used to diagnose myocardial infarction (heart attack) and to assess the extent of heart muscle damage.
Background[edit | edit source]
Creatine kinase is an enzyme found in various tissues, including the heart, brain, and skeletal muscle. It plays a crucial role in energy production by catalyzing the conversion of creatine and utilizing adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). CK has three isoenzymes: CK-MM, CK-BB, and CK-MB. The CK-MB isoenzyme is predominantly found in cardiac muscle, making it a useful marker for heart muscle damage.
Clinical Use[edit | edit source]
The CPK-MB test is particularly useful in the context of acute coronary syndrome (ACS) and suspected myocardial infarction. When heart muscle is damaged, as in the case of a heart attack, CK-MB is released into the bloodstream. Measuring the levels of CK-MB can help determine the presence and severity of a myocardial infarction.
Procedure[edit | edit source]
The test involves drawing a blood sample from a vein, usually in the arm. The blood is then analyzed in a laboratory to measure the concentration of CK-MB. Elevated levels of CK-MB in the blood can indicate heart muscle damage.
Interpretation[edit | edit source]
- Normal Range: The normal range for CK-MB is typically 0-5 ng/mL, but this can vary slightly depending on the laboratory. - Elevated Levels: Elevated CK-MB levels suggest myocardial damage. Levels typically rise within 4-6 hours after a heart attack, peak at 12-24 hours, and return to normal within 48-72 hours.
Limitations[edit | edit source]
While the CPK-MB test is useful, it is not as specific as newer markers such as troponin. CK-MB can also be elevated in conditions other than myocardial infarction, such as myocarditis, pericarditis, and muscular dystrophy.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
