CM-4620

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Chemical compound



CM-4620 is a chemical compound that has been studied for its potential therapeutic effects, particularly in the context of calcium channel modulation. It is a small molecule that acts as an inhibitor of the calcium release-activated calcium channel (CRAC), which plays a crucial role in various cellular processes.

Chemical Structure[edit | edit source]

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Structure of CM-4620

CM-4620 is characterized by its unique chemical structure, which allows it to interact specifically with the CRAC channels. The structure of CM-4620 includes several functional groups that are essential for its activity and specificity.

Mechanism of Action[edit | edit source]

CM-4620 functions primarily as a CRAC channel inhibitor. CRAC channels are integral to the process of calcium signaling in cells, which is vital for numerous physiological functions, including muscle contraction, neurotransmitter release, and gene expression. By inhibiting these channels, CM-4620 can modulate calcium influx into cells, thereby influencing these processes.

Potential Therapeutic Applications[edit | edit source]

The inhibition of CRAC channels by CM-4620 has been explored for its potential in treating various conditions. These include:

Research and Development[edit | edit source]

Research on CM-4620 is ongoing, with studies focusing on its pharmacokinetics, safety profile, and efficacy in various disease models. Clinical trials are being conducted to better understand its potential benefits and limitations in human subjects.

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Contributors: Prab R. Tumpati, MD