COPP (chemotherapy)

COPP (chemotherapy)

The COPP regimen is a chemotherapy treatment protocol primarily used in the treatment of Hodgkin's lymphoma. The acronym COPP stands for the drugs that make up the regimen: Cyclophosphamide, Oncovin, Procarbazine, and Prednisone.

Treatment Protocol

The COPP regimen is typically administered in cycles, with each cycle lasting 28 days. The drugs are administered as follows:

• Cyclophosphamide: Given orally on days 1-14 of the cycle.
• Oncovin (Vincristine): Given intravenously on days 1 and 8 of the cycle.
• Procarbazine: Given orally on days 1-14 of the cycle.
• Prednisone: Given orally on days 1-14 of the cycle.

The exact dosage and duration of treatment may vary depending on the patient's overall health, the stage of the disease, and the treating physician's discretion.

Side Effects

Like all chemotherapy regimens, the COPP regimen can cause side effects. These may include nausea, vomiting, hair loss, fatigue, and neutropenia. Patients may also experience steroid-induced diabetes due to the use of Prednisone.

Efficacy

The COPP regimen has been shown to be effective in the treatment of Hodgkin's lymphoma, with many patients achieving complete remission. However, the regimen is also associated with a high rate of infertility, particularly in male patients.

See Also

• Chemotherapy
• Hodgkin's lymphoma
• Cyclophosphamide
• Oncovin
• Procarbazine
• Prednisone