CUMYL-NBMINACA
Overview[edit | edit source]
CUMYL-NBMINACA is a synthetic cannabinoid that acts as a potent agonist of the cannabinoid receptors. It is part of a class of compounds that are often used in the manufacture of designer drugs. These substances are designed to mimic the effects of tetrahydrocannabinol (THC), the active component of cannabis.
Chemical Properties[edit | edit source]
CUMYL-NBMINACA is chemically classified as an indazole-based synthetic cannabinoid. Its full chemical name is N-(1-(cyclohexylmethyl)-1''H''-indazole-3-carbonyl)-L-valine methyl ester. The compound is known for its high affinity for the CB1 receptor, which is primarily responsible for the psychoactive effects associated with cannabinoids.
Pharmacology[edit | edit source]
CUMYL-NBMINACA functions as a full agonist at the CB1 receptor and CB2 receptor, with a higher selectivity for the CB1 receptor. This selectivity contributes to its potent psychoactive effects. The compound's interaction with these receptors can lead to a range of effects, including euphoria, anxiety, and hallucinations.
Usage and Effects[edit | edit source]
Synthetic cannabinoids like CUMYL-NBMINACA are often sprayed onto plant material and sold as "herbal incense" or "spice". Users typically smoke the treated plant material to achieve a high similar to that of cannabis. However, the effects can be unpredictable and sometimes more intense, leading to adverse reactions such as tachycardia, hypertension, and seizures.
Legal Status[edit | edit source]
Due to its potential for abuse and lack of medical use, CUMYL-NBMINACA is classified as a controlled substance in many countries. Regulatory agencies have placed it under various schedules to restrict its distribution and use. The compound is often included in legislation targeting synthetic cannabinoids as a class.
Health Risks[edit | edit source]
The use of CUMYL-NBMINACA has been associated with numerous health risks. Acute intoxication can result in severe psychosis, agitation, and cardiovascular complications. Long-term use may lead to addiction and withdrawal symptoms. The variability in potency and purity of synthetic cannabinoids further exacerbates these risks.
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