CYREN (protein)

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Ideogram human chromosome 7

CYREN (protein)

CYREN is a protein that plays a crucial role in cellular processes. It is a key component in the regulation of DNA repair mechanisms and cell cycle progression. The name CYREN stands for "Cell Cycle Regulator of Endonuclease V."

Function[edit | edit source]

CYREN functions as a regulator of endonuclease V, an enzyme involved in DNA repair. It is essential for maintaining genomic stability and preventing mutations that can lead to diseases such as cancer. Additionally, CYREN is involved in controlling the cell cycle, ensuring that cells divide properly and avoid abnormalities.

Structure[edit | edit source]

The structure of CYREN consists of multiple domains that interact with other proteins and DNA molecules. These interactions are essential for its function in DNA repair and cell cycle regulation. Studies have shown that mutations in the gene encoding CYREN can disrupt its structure and impair its ability to perform its functions effectively.

Role in Disease[edit | edit source]

Mutations in the gene encoding CYREN have been associated with various diseases, including cancer. Dysregulation of CYREN can lead to defects in DNA repair mechanisms, increasing the risk of genomic instability and tumorigenesis. Understanding the role of CYREN in disease development is crucial for developing targeted therapies to treat these conditions.

Research[edit | edit source]

Research on CYREN is ongoing to elucidate its precise mechanisms of action and its potential as a therapeutic target. Scientists are investigating how CYREN interacts with other proteins and DNA to maintain genomic stability and prevent disease. By studying CYREN, researchers aim to uncover new insights into the molecular pathways involved in DNA repair and cell cycle regulation.

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD