Cafestol

Cafestol is a diterpene molecule present in coffee. A potent LDL cholesterol elevating compound, it is found in highest quantity in unfiltered coffee drinks. Studies have shown that cafestol affects the body's ability to metabolize and regulate cholesterol.

Chemical Structure

Cafestol is a member of the diterpene family of organic compounds. It is structurally similar to other diterpenes, with a molecular formula of C20H28O3.

Health Effects

Cafestol has been found to have both beneficial and harmful effects on health. It has been shown to be a potent elevating agent of plasma cholesterol levels in humans. However, it also has potential anticarcinogenic properties, particularly in relation to colorectal cancer.

Cholesterol

Cafestol is one of the most potent cholesterol elevating compounds found in the human diet. It increases the levels of LDL cholesterol in the body by suppressing the activity of a liver receptor that regulates cholesterol levels.

Cancer

Studies have suggested that cafestol may have anticarcinogenic properties. It has been found to inhibit the growth of cancer cells in vitro and in animal models.

Sources

Cafestol is found in the oily part of coffee, and is therefore present in higher amounts in unfiltered coffee drinks such as French press coffee or Turkish coffee. It is also found in espresso, but in lower amounts due to the filtering process.

See Also

• Coffee
• Diterpene
• Cholesterol
• Cancer

Cafestol Resources
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