Calcium carbimide
Calcium Carbimide[edit | edit source]
Calcium carbimide is a chemical compound used primarily in the treatment of alcohol dependence. It acts as an alcohol deterrent by interfering with the metabolism of alcohol, leading to unpleasant effects when alcohol is consumed.
Mechanism of Action[edit | edit source]
Calcium carbimide works by inhibiting the enzyme acetaldehyde dehydrogenase, which is responsible for the breakdown of acetaldehyde, a toxic metabolite of ethanol. When acetaldehyde dehydrogenase is inhibited, acetaldehyde accumulates in the blood, causing symptoms such as flushing, nausea, and palpitations. These symptoms are intended to deter individuals from consuming alcohol.
Clinical Use[edit | edit source]
Calcium carbimide is used as part of a comprehensive treatment program for alcohol dependence. It is typically administered orally in tablet form. The drug is most effective when combined with counseling and support groups, as it helps to reinforce the desire to abstain from alcohol.
Side Effects[edit | edit source]
Common side effects of calcium carbimide include:
- Flushing
- Nausea
- Vomiting
- Headache
- Dizziness
These side effects are more pronounced when alcohol is consumed. Patients are advised to avoid alcohol completely while taking calcium carbimide.
Contraindications[edit | edit source]
Calcium carbimide is contraindicated in individuals with:
- Severe cardiovascular disease
- Severe respiratory disease
- Hypersensitivity to the drug
Related Compounds[edit | edit source]
Calcium carbimide is similar in function to disulfiram, another alcohol deterrent. Both drugs work by inhibiting acetaldehyde dehydrogenase, but they differ in their chemical structure and pharmacokinetics.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
