Carla V. Rothlin

Carla V. Rothlin

Carla Rothlin at National Institutes of Health

Carla V. Rothlin is an Argentine-American immunologist known for her pioneering work in the field of immunology, particularly in understanding the mechanisms of immune regulation and resolution of inflammation. She is a professor at Yale University, where she conducts research on the molecular pathways that control immune responses.

Early Life and Education

Carla V. Rothlin was born in Argentina, where she developed an early interest in the biological sciences. She pursued her undergraduate studies in biochemistry at the University of Buenos Aires, where she graduated with honors. Her passion for understanding the immune system led her to pursue a Ph.D. in immunology at the same institution.

Career

After completing her doctoral studies, Rothlin moved to the United States to further her research in immunology. She joined the laboratory of Gregory Lemke at the Salk Institute for Biological Studies in La Jolla, California, as a postdoctoral fellow. During her time at the Salk Institute, Rothlin made significant contributions to the understanding of the TAM receptor tyrosine kinases, a family of receptors that play a crucial role in the regulation of immune responses.

In 2009, Rothlin joined the faculty at Yale University as an assistant professor in the Department of Immunobiology. Her research at Yale has focused on the molecular mechanisms that regulate the resolution of inflammation, a critical process in preventing chronic inflammatory diseases.

Research Contributions

Rothlin's research has significantly advanced the understanding of how the immune system resolves inflammation. Her work on the TAM receptor family, which includes Tyro3, Axl, and Mer, has elucidated how these receptors help to clear apoptotic cells and dampen inflammatory responses. This research has important implications for the treatment of autoimmune diseases and chronic inflammatory conditions.

Rothlin's laboratory has also explored the role of these receptors in cancer, where they may contribute to the immune system's ability to recognize and eliminate tumor cells. Her findings have opened new avenues for therapeutic interventions targeting these pathways.

Awards and Honors

Carla V. Rothlin has received numerous awards for her contributions to immunology. She has been recognized by the American Association of Immunologists and has received several prestigious grants to support her research. Her work continues to influence the field of immunology and inspire new research into immune regulation.

Personal Life

Rothlin is known for her dedication to mentoring young scientists and fostering a collaborative research environment. She is actively involved in various scientific communities and frequently participates in conferences and workshops to share her insights and findings.

Related Pages

• Immunology
• Inflammation
• TAM receptor
• Yale University