Catagen
Catagen[edit | edit source]
The catagen phase is a short transitional stage of the hair growth cycle that follows the active growth phase, known as the anagen phase, and precedes the resting phase, known as the telogen phase. During the catagen phase, hair growth ceases, and the hair follicle undergoes significant changes that prepare it for the subsequent shedding and renewal process.
Overview[edit | edit source]
The catagen phase is a critical part of the hair growth cycle, although it is relatively brief compared to the other phases. It typically lasts for about 2 to 3 weeks. During this time, the hair follicle shrinks and detaches from the dermal papilla, which is the structure that supplies nutrients to the growing hair. This detachment marks the end of active hair growth.
Biological Process[edit | edit source]
During the catagen phase, several key biological processes occur:
- Apoptosis: The cells in the lower part of the hair follicle undergo programmed cell death, or apoptosis. This process is essential for the regression of the hair follicle.
- Follicle Shrinkage: The hair follicle shrinks to about one-sixth of its original length. This shrinkage is due to the breakdown of the outer root sheath and the cessation of cell proliferation.
- Formation of the Club Hair: As the follicle shrinks, the hair shaft becomes a "club hair," which is a hair that is no longer growing and is ready to be shed during the telogen phase.
Significance[edit | edit source]
The catagen phase is crucial for the renewal of hair follicles. It allows the hair follicle to reset and prepare for the next cycle of growth. Disruptions in the catagen phase can lead to hair disorders, such as alopecia, where the normal hair growth cycle is altered.
Clinical Relevance[edit | edit source]
Understanding the catagen phase is important in the study of hair loss treatments and hair restoration techniques. By targeting the molecular pathways involved in the catagen phase, researchers aim to develop therapies that can prolong the anagen phase or prevent premature entry into the catagen phase, thereby promoting healthier hair growth.
Also see[edit | edit source]
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