Cataract congenital dominant non nuclear
=Cataract Congenital Dominant Non-Nuclear =
Cataract Congenital Dominant Non-Nuclear is a rare genetic disorder characterized by the development of cataracts at birth or during early childhood. Unlike other types of cataracts, this condition specifically affects the non-nuclear regions of the lens, sparing the central nucleus. This article provides a comprehensive overview of the condition, including its Causes, Symptoms, Diagnosis, Treatment, and Prognosis.
Causes[edit | edit source]
Cataract Congenital Dominant Non-Nuclear is primarily caused by genetic mutations. It is inherited in an autosomal dominant pattern, meaning a single copy of the mutated gene from an affected parent can cause the disorder. Several genes have been implicated in this condition, including mutations in the CRYAA and CRYBB2 genes, which encode crystallin proteins essential for lens transparency and structure.
Symptoms[edit | edit source]
The primary symptom of Cataract Congenital Dominant Non-Nuclear is the presence of cataracts at birth or early childhood. These cataracts are typically located in the cortical or subcapsular regions of the lens, leaving the central nucleus clear. Symptoms may include:
- Blurred vision
- Glare or halos around lights
- Difficulty seeing in low light conditions
- Nystagmus (involuntary eye movements) in severe cases
Diagnosis[edit | edit source]
Diagnosis of Cataract Congenital Dominant Non-Nuclear involves a thorough eye examination by an ophthalmologist. Key diagnostic procedures include:
- Slit-lamp examination to assess the location and extent of the cataract
- Genetic testing to identify specific mutations associated with the condition
- Family history analysis to determine inheritance patterns
Treatment[edit | edit source]
Treatment for Cataract Congenital Dominant Non-Nuclear depends on the severity of the cataract and its impact on vision. Options include:
- Monitoring: Regular eye exams to track cataract progression
- Surgery: Cataract extraction and lens replacement if vision is significantly impaired
- Visual aids: Glasses or contact lenses to correct refractive errors
Prognosis[edit | edit source]
The prognosis for individuals with Cataract Congenital Dominant Non-Nuclear varies. Early detection and treatment can lead to good visual outcomes. However, untreated cataracts can result in amblyopia (lazy eye) or permanent vision loss. Genetic counseling is recommended for affected families to understand the risks of transmission to offspring.
See Also[edit | edit source]
External Links[edit | edit source]
- Genetic and Rare Diseases Information Center
- [National Eye Institute](https://www.nei.nih.gov/)
NIH genetic and rare disease info[edit source]
Cataract congenital dominant non nuclear is a rare disease.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
