Cementogenesis

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Cementogenesis is a process that involves the formation of cementum, a calcified substance that covers the root of a tooth. This process is essential for the function and stability of teeth, as it allows for the attachment of periodontal ligament fibers to the tooth surface, which in turn facilitates tooth anchorage to the surrounding alveolar bone.

Process[edit | edit source]

Cementogenesis begins when Hertwig's epithelial root sheath (HERS), a structure responsible for shaping the root of the tooth, disintegrates. This disintegration allows for undifferentiated mesenchymal cells in the dental follicle to come into contact with the newly formed root dentin. These cells differentiate into cementoblasts, which are responsible for the secretion of cementum.

Cementum is primarily composed of hydroxyapatite, a hard, bone-like substance, and is continuously deposited throughout the life of the tooth. This continuous deposition allows for the repair of the root surface and the adaptation to occlusal forces.

Types of Cementum[edit | edit source]

There are two main types of cementum: acellular cementum and cellular cementum. Acellular cementum is the first to be formed and covers the cervical half of the root. It does not contain cells and is primarily responsible for attaching the tooth to the alveolar bone. Cellular cementum, on the other hand, is formed after the tooth has erupted and covers the apical half of the root. It contains cementocytes and is less calcified than acellular cementum.

Clinical Significance[edit | edit source]

Cementogenesis has significant implications in dental health. Abnormalities in cementum formation can lead to periodontal disease, tooth loss, and other dental problems. Furthermore, understanding the process of cementogenesis can aid in the development of treatments for these conditions.

See Also[edit | edit source]

References[edit | edit source]


Cementogenesis Resources
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Contributors: Prab R. Tumpati, MD