Ceprotin

From WikiMD's Wellness Encyclopedia

Ceprotin is a brand name for a medication known as protein C concentrate. It is used in the treatment of protein C deficiency, a rare genetic disorder that can lead to severe blood clotting issues. Ceprotin is manufactured by Baxter International and is administered via intravenous injection.

Medical Uses[edit | edit source]

Ceprotin is primarily indicated for patients with severe congenital protein C deficiency. This condition can result in purpura fulminans, a life-threatening disorder characterized by blood clotting and skin necrosis. Ceprotin helps to replace the missing or malfunctioning protein C, thereby reducing the risk of clot formation and associated complications.

Mechanism of Action[edit | edit source]

Protein C is a vitamin K-dependent anticoagulant protein that plays a crucial role in regulating blood clotting. It works by inactivating factors Va and VIIIa, which are essential for the clotting process. By supplementing protein C levels, Ceprotin helps to restore the natural balance of clot formation and dissolution in the body.

Administration[edit | edit source]

Ceprotin is administered intravenously, typically in a hospital setting. The dosage and frequency of administration depend on the severity of the protein C deficiency and the patient's clinical condition. Regular monitoring of protein C levels and clotting parameters is essential to ensure effective treatment.

Side Effects[edit | edit source]

Common side effects of Ceprotin include injection site reactions, such as redness and swelling. More serious side effects can include allergic reactions, such as anaphylaxis, and the development of antibodies against protein C, which can reduce the effectiveness of the treatment.

Related Conditions[edit | edit source]

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD