Cetrimonium bromide

Cetrimonium bromide (also known as CTAB and hexadecyltrimethylammonium bromide) is a quaternary ammonium compound used for a variety of purposes in the pharmaceutical industry, cosmetics industry, and laboratory research. It is a cationic surfactant, and in pharmaceuticals, it is often used as a topical antiseptic.

Chemical Structure and Properties

Cetrimonium bromide is a quaternary ammonium compound with the chemical formula C19H42BrN. It is a white, crystalline powder that is soluble in water and alcohol. The compound has a strong positive charge, which allows it to interact with negatively charged substances, such as DNA and proteins.

Uses

Pharmaceutical Industry

In the pharmaceutical industry, cetrimonium bromide is used as a topical antiseptic and a component of some types of eye drops. It is also used as an excipient in various pharmaceutical formulations.

Cosmetics Industry

In the cosmetics industry, cetrimonium bromide is used as a surfactant and emulsifying agent. It is commonly found in hair conditioners and lotions, where it helps to improve texture and ease of application.

Laboratory Research

In laboratory research, cetrimonium bromide is used as a reagent in the extraction and purification of DNA. It is also used in the study of protein structure and function.

Safety and Toxicity

Cetrimonium bromide is generally considered safe for topical use. However, it can cause skin irritation in some individuals, and should not be ingested or inhaled. In laboratory studies, it has been shown to be toxic to aquatic life.

See Also

• Quaternary ammonium compounds
• Surfactant
• Antiseptic