Chloroacetone

From WikiMD's Wellness Encyclopedia

FeistBenarysynthesis.gif|thumb]] Chloroacetone is a chemical compound with the formula C3H5ClO. It is a colorless liquid with a pungent odor and is a powerful lachrymator. Chloroacetone is used in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is also historically known for its use as a tear gas in World War I.

Production[edit | edit source]

Chloroacetone is produced by the chlorination of acetone with chlorine gas in the presence of a catalyst, typically at elevated temperatures. The reaction can produce several by-products, so careful control of reaction conditions is necessary to maximize the yield of chloroacetone.

Uses[edit | edit source]

Organic Synthesis[edit | edit source]

In organic chemistry, chloroacetone is a versatile intermediate. It is used in the synthesis of various pharmaceuticals, including analgesics, antipyretics, and antibiotics. It also serves as a precursor to pesticides and herbicides, demonstrating its importance in the agricultural industry.

Military Use[edit | edit source]

During World War I, chloroacetone was used as a tear gas. Its lachrymatory (tear-producing) effect made it effective for incapacitating enemy troops. However, its use in warfare is now largely prohibited under various international conventions.

Safety[edit | edit source]

Chloroacetone is a potent irritant to the eyes, skin, and respiratory system. It can cause severe eye and respiratory tract irritation, leading to tearing and coughing. Prolonged exposure can result in more serious health effects, including lung damage. Appropriate safety measures, including the use of personal protective equipment (PPE), are essential when handling chloroacetone.

Environmental Impact[edit | edit source]

The environmental impact of chloroacetone is associated with its toxicity to aquatic life. It should be handled with care to prevent release into the environment, where it can have harmful effects on aquatic organisms.

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD