Cod-THC

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Tetrahydrocannabinol (THC)[edit | edit source]

Chemical structure of THC

Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis. It is one of at least 113 cannabinoids identified in cannabis. THC is the substance primarily responsible for the effects of cannabis on the human central nervous system.

Chemical Properties[edit | edit source]

THC is a hydrophobic compound, meaning it does not dissolve in water but is soluble in most organic solvents. Its chemical formula is C21H30O2, and it has a molecular weight of 314.47 g/mol. The compound is a terpenoid, which is a class of naturally occurring organic chemicals derived from terpenes.

Pharmacology[edit | edit source]

THC exerts its effects by binding to the cannabinoid receptors in the brain. These receptors are part of the endocannabinoid system, which plays a role in regulating mood, memory, appetite, and pain sensation. The two main types of cannabinoid receptors are CB1 and CB2. THC has a higher affinity for CB1 receptors, which are primarily located in the brain and central nervous system.

Effects on the Human Body[edit | edit source]

THC is the main psychoactive component of cannabis.

The effects of THC on the human body can vary depending on the dose, method of consumption, and individual differences. Common effects include euphoria, relaxation, altered perception of time, and increased appetite. In some cases, THC can cause anxiety, paranoia, or impaired memory and coordination.

Medical Uses[edit | edit source]

THC has been used for its medicinal properties in various treatments. It is known to help alleviate chronic pain, reduce nausea and vomiting in patients undergoing chemotherapy, and stimulate appetite in individuals with HIV/AIDS. THC is also being studied for its potential benefits in treating conditions such as multiple sclerosis and epilepsy.

Legal Status[edit | edit source]

The legal status of THC varies widely around the world. In some countries, it is classified as a controlled substance, while in others, it is legal for medical or recreational use. The United States has a complex legal framework where THC is illegal at the federal level but legal in some states for medical or recreational use.

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Contributors: Prab R. Tumpati, MD