Medrogestone

Medrogestone.svg

Synthetic progestogen

Medrogestone is a synthetic progestogen with similar properties to the natural hormone progesterone. It is used in hormone replacement therapy and for the treatment of gynecological disorders such as endometriosis and menstrual disorders.

Pharmacology

Medrogestone acts on the progesterone receptors in the body, mimicking the effects of natural progesterone. It helps regulate the menstrual cycle and maintain the endometrium in a state suitable for pregnancy. It also has anti-estrogenic effects, which can be beneficial in treating conditions like endometriosis.

Medical Uses

Medrogestone is primarily used in hormone replacement therapy for menopausal women to alleviate symptoms such as hot flashes, vaginal atrophy, and osteoporosis. It is also used to treat menstrual disorders like dysmenorrhea and menorrhagia, as well as endometriosis.

Side Effects

Common side effects of medrogestone include nausea, breast tenderness, headache, and mood changes. Long-term use may increase the risk of thrombosis, stroke, and breast cancer.

Chemistry

Medrogestone is a synthetic derivative of progesterone. Its chemical structure allows it to bind effectively to progesterone receptors, exerting similar biological effects.

See Also

• Progesterone
• Hormone replacement therapy
• Endometriosis
• Menstrual disorders