Medrogestone
Synthetic progestogen
| Medrogestone | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | Oral |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | 977-79-7 |
| PubChem | 68870 |
| DrugBank | DB08982 |
| ChemSpider | 62078 |
| KEGG | D01275 |
Medrogestone is a synthetic progestogen with similar properties to the natural hormone progesterone. It is used in hormone replacement therapy and for the treatment of gynecological disorders such as endometriosis and menstrual disorders.
Pharmacology[edit | edit source]
Medrogestone acts on the progesterone receptors in the body, mimicking the effects of natural progesterone. It helps regulate the menstrual cycle and maintain the endometrium in a state suitable for pregnancy. It also has anti-estrogenic effects, which can be beneficial in treating conditions like endometriosis.
Medical Uses[edit | edit source]
Medrogestone is primarily used in hormone replacement therapy for menopausal women to alleviate symptoms such as hot flashes, vaginal atrophy, and osteoporosis. It is also used to treat menstrual disorders like dysmenorrhea and menorrhagia, as well as endometriosis.
Side Effects[edit | edit source]
Common side effects of medrogestone include nausea, breast tenderness, headache, and mood changes. Long-term use may increase the risk of thrombosis, stroke, and breast cancer.
Chemistry[edit | edit source]
Medrogestone is a synthetic derivative of progesterone. Its chemical structure allows it to bind effectively to progesterone receptors, exerting similar biological effects.
See Also[edit | edit source]
References[edit | edit source]
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