Coriobacteriia

Coriobacteriia is a class of Gram-positive bacteria within the phylum Actinomycetota. These bacteria are known for their role in the human gut microbiome and their ability to metabolize complex carbohydrates and other substrates.

Characteristics

Coriobacteriia are typically non-motile and non-spore-forming. They are anaerobic or facultatively anaerobic, meaning they can survive in environments with or without oxygen. The cells are usually rod-shaped or coccoid, and they often form part of the normal flora of the gastrointestinal tract in humans and other animals.

Ecological Role

Coriobacteriia play a significant role in the digestion of complex carbohydrates and the metabolism of bile acids and steroids. They are involved in the fermentation processes in the gut, contributing to the production of short-chain fatty acids, which are important for gut health. These bacteria also participate in the transformation of dietary compounds and xenobiotics, influencing the bioavailability and activity of these substances.

Clinical Significance

While Coriobacteriia are generally considered commensal organisms, they can become opportunistic pathogens under certain conditions. They have been implicated in infections such as bacteremia and endocarditis, particularly in immunocompromised individuals. Understanding the balance of Coriobacteriia in the gut microbiome is important for maintaining health and preventing disease.

Taxonomy

The class Coriobacteriia includes several orders, families, and genera. Some of the notable genera include:

• Eggerthella
• Gordonibacter
• Atopobium

Research and Applications

Research into Coriobacteriia is ongoing, with studies focusing on their role in health and disease, their metabolic capabilities, and their potential use in biotechnology. These bacteria are of interest for their ability to transform complex organic compounds, which could have applications in bioremediation and the production of bioactive compounds.

Also see

• Gut microbiota
• Actinomycetota
• Bacterial taxonomy
• Microbial metabolism