Corticotropin
Corticotropin is a hormone produced by the pituitary gland. It is also known as adrenocorticotropic hormone (ACTH). This hormone stimulates the adrenal glands to release cortisol, a steroid hormone that helps the body respond to stress.
Function[edit | edit source]
Corticotropin is part of the body's response to physical or emotional stress. The hypothalamus, a part of the brain, releases corticotropin-releasing hormone (CRH) when it detects stress. CRH then triggers the pituitary gland to produce and release corticotropin. Once released into the bloodstream, corticotropin travels to the adrenal glands, where it stimulates the release of cortisol.
Cortisol has many functions in the body. It helps to maintain blood pressure and cardiovascular function, reduce the immune system's response to inflammation, balance the effects of insulin in breaking down sugar for energy, and regulate the metabolism of proteins, carbohydrates, and fats.
[edit | edit source]
Disorders related to corticotropin include Cushing's syndrome, Addison's disease, and Adrenal insufficiency. These disorders can occur if the body produces too much or too little corticotropin.
Cushing's syndrome is a condition that occurs when the body produces too much cortisol. This can occur if the pituitary gland produces too much corticotropin. Symptoms of Cushing's syndrome can include weight gain, thinning skin, and fatigue.
Addison's disease is a condition that occurs when the body does not produce enough cortisol. This can occur if the pituitary gland does not produce enough corticotropin. Symptoms of Addison's disease can include weight loss, muscle weakness, and low blood pressure.
Adrenal insufficiency is a condition that occurs when the adrenal glands do not produce enough cortisol. This can occur if the pituitary gland does not produce enough corticotropin. Symptoms of adrenal insufficiency can include fatigue, muscle weakness, and low blood pressure.
See also[edit | edit source]
Corticotropin Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD