Cromolyn

Cromolyn is a medication used to manage and prevent allergic reactions and asthma. It is classified as a mast cell stabilizer, which works by preventing the release of substances that cause inflammation and allergic symptoms.

Medical Uses

Cromolyn is primarily used for the following conditions:

• Asthma: It is used as a preventive treatment for chronic asthma.
• Allergic rhinitis: Cromolyn can be used to treat symptoms of nasal allergies.
• Allergic conjunctivitis: It is effective in managing eye allergies.
• Mastocytosis: Cromolyn helps in reducing symptoms associated with this condition.

Mechanism of Action

Cromolyn works by inhibiting the release of histamine and other inflammatory mediators from mast cells. This action helps to prevent the inflammatory response that leads to symptoms of asthma and allergies.

Administration

Cromolyn is available in various forms, including:

• Inhaler: For asthma management.
• Nasal spray: For allergic rhinitis.
• Eye drops: For allergic conjunctivitis.
• Oral solution: For systemic mastocytosis.

Side Effects

Common side effects of cromolyn include:

• Cough
• Throat irritation
• Nasal irritation
• Eye irritation

History

Cromolyn was first discovered in the 1960s by British pharmacologist Roger Altounyan, who was researching treatments for asthma. It was derived from a natural substance found in the plant Ammi visnaga.

Related Pages

• Asthma
• Allergic rhinitis
• Allergic conjunctivitis
• Mastocytosis
• Histamine
• Mast cell