Cuffitis

From WikiMD's Wellness Encyclopedia


Cuffitis
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Rectal bleeding, abdominal pain, diarrhea
Complications Pouch failure
Onset Post-surgical
Duration Chronic
Types N/A
Causes Inflammation of the rectal cuff
Risks Ulcerative colitis, Familial adenomatous polyposis
Diagnosis Endoscopy, Biopsy
Differential diagnosis N/A
Prevention N/A
Treatment Topical therapy, Oral medication
Medication N/A
Prognosis N/A
Frequency Common in patients with ileal pouch-anal anastomosis
Deaths N/A


Cuffitis is an inflammatory condition affecting the rectal cuff in patients who have undergone ileal pouch-anal anastomosis (IPAA), a surgical procedure often performed for individuals with ulcerative colitis or familial adenomatous polyposis.

Symptoms[edit | edit source]

Patients with cuffitis typically experience symptoms such as rectal bleeding, abdominal pain, and diarrhea. These symptoms can significantly impact the quality of life and may resemble those of pouchitis, another complication of IPAA.

Causes[edit | edit source]

Cuffitis is caused by inflammation of the rectal cuff, which is the small segment of rectum left after the removal of the colon and rectum during IPAA. The inflammation can be due to residual ulcerative colitis in the cuff or other inflammatory processes.

Diagnosis[edit | edit source]

The diagnosis of cuffitis is typically made through endoscopy, where a visual examination of the rectal cuff is performed. A biopsy may also be taken to confirm the presence of inflammation and to rule out other conditions.

Treatment[edit | edit source]

Treatment for cuffitis often involves topical therapy with steroid or 5-aminosalicylic acid (5-ASA) suppositories or enemas. In some cases, oral medication may be prescribed to manage the inflammation. It is important to differentiate cuffitis from pouchitis as the treatment strategies may differ.

Complications[edit | edit source]

If left untreated, cuffitis can lead to complications such as pouch failure, which may necessitate further surgical intervention.

See also[edit | edit source]

References[edit | edit source]


External links[edit | edit source]

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Contributors: Prab R. Tumpati, MD