D-calcium pantothenate
D-Calcium Pantothenate is a chemical compound and a salt form of pantothenic acid (vitamin B5). It is commonly used in dietary supplements and fortified foods to provide a stable source of vitamin B5. Pantothenic acid is an essential nutrient that plays a key role in the synthesis and metabolism of proteins, carbohydrates, and fats. It is also involved in the production of red blood cells and steroid hormones, and it aids in the maintenance of a healthy digestive tract.
Chemical Properties[edit | edit source]
D-Calcium Pantothenate is the calcium salt of the dextrorotatory isomer of pantothenic acid. It is more stable than pantothenic acid itself, making it a preferred choice for use in vitamin supplements and fortified foods. The compound is white to off-white, crystalline, and has a slight characteristic odor. It is soluble in water and slightly soluble in alcohol.
Health Benefits[edit | edit source]
The primary health benefit of D-Calcium Pantothenate is its role in the synthesis of coenzyme A (CoA), which is essential for fatty acid metabolism. This makes it crucial for energy production within cells. Additionally, it supports the synthesis of acetylcholine, a neurotransmitter important for brain function. Vitamin B5 also aids in wound healing, and it has been studied for its potential to lower cholesterol levels and improve heart health.
Sources and Requirements[edit | edit source]
While pantothenic acid is found in a variety of foods, including meats, vegetables, cereals, legumes, eggs, and milk, D-Calcium Pantothenate is often added to food products and used in dietary supplements to ensure adequate intake. The recommended daily allowance (RDA) for adults is 5 mg of pantothenic acid per day. However, requirements may vary based on age, gender, and health status.
Deficiency[edit | edit source]
Deficiency in pantothenic acid is rare due to its widespread availability in food. However, symptoms of deficiency can include fatigue, insomnia, depression, irritability, vomiting, stomach pains, burning feet, and upper respiratory infections.
Use in Supplements and Fortified Foods[edit | edit source]
D-Calcium Pantothenate is widely used in the formulation of dietary supplements, either as a standalone vitamin B5 supplement or as part of a B-complex or multivitamin product. It is also added to fortified foods such as breakfast cereals, energy bars, and beverages to enhance their nutritional value.
Safety and Side Effects[edit | edit source]
D-Calcium Pantothenate is generally considered safe when taken in recommended doses. Side effects are rare but may include mild digestive disturbances in some individuals. High doses may lead to diarrhea or an increased risk of bleeding.
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Contributors: Prab R. Tumpati, MD