DAN (protein)
DAN (protein) is a protein that in humans is encoded by the DAN gene. It is a member of the DAN family of secreted proteins, which are involved in suppressing bone morphogenetic protein (BMP) signaling pathways.
Function[edit | edit source]
The DAN gene is a member of the DAN family of bone morphogenetic protein (BMP) antagonists. The protein product of the DAN gene is a secreted glycoprotein that is involved in the regulation of cell proliferation and differentiation. It functions by binding to BMPs and preventing them from interacting with their receptors, thereby inhibiting BMP signaling pathways.
Clinical significance[edit | edit source]
Mutations in the DAN gene have been associated with various diseases, including cancer and certain genetic disorders. For example, overexpression of the DAN gene has been observed in some types of cancer, suggesting that it may play a role in tumor progression.
See also[edit | edit source]
References[edit | edit source]
 | This protein-related article is a stub. You can help WikiMD by expanding it. |
 | This gene article is a stub. You can help WikiMD by expanding it. |
 | This cell biology article is a stub. You can help WikiMD by expanding it. |
 | This oncology article is a stub. You can help WikiMD by expanding it. |
 | This genetics article is a stub. You can help WikiMD by expanding it. |
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD
