DHSA

DHSA

DHSA (Dihydroxy Stearic Acid) is a type of fatty acid that is derived from the hydrogenation of oleic acid. It is a saturated fatty acid with two hydroxyl groups, which gives it unique chemical properties and applications in various industries.

Metabolic pathway of DHSA

Chemical Structure

DHSA is a long-chain fatty acid with the chemical formula C₁₈H₃₆O₄. It is characterized by the presence of two hydroxyl groups attached to the carbon chain, which are typically located at the 9th and 10th carbon positions. This dihydroxylation makes DHSA more polar than its parent compound, stearic acid.

Production

DHSA is produced through the chemical modification of oleic acid, a monounsaturated fatty acid commonly found in vegetable oils. The process involves the catalytic hydrogenation of oleic acid, followed by hydroxylation. This process can be carried out using various catalysts and conditions to optimize yield and purity.

Applications

Due to its unique properties, DHSA is used in a variety of applications:

• Cosmetics and Personal Care: DHSA is used as an emollient and thickening agent in creams, lotions, and other personal care products. Its ability to retain moisture makes it valuable in formulations designed to hydrate and protect the skin.

• Industrial Uses: In the industrial sector, DHSA is used as a plasticizer and lubricant. Its hydroxyl groups allow it to interact with other chemical compounds, enhancing the flexibility and durability of materials.

• Pharmaceuticals: DHSA is also explored for its potential use in drug delivery systems due to its biocompatibility and ability to form stable emulsions.

Biological Role

In biological systems, DHSA can be metabolized by certain enzymes and may play a role in lipid metabolism. Its presence in the body is typically a result of dietary intake of fats and oils that contain oleic acid.

Related Pages

• Fatty acid
• Oleic acid
• Stearic acid
• Hydrogenation