DMCPA

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DMCPA


Dichloromethylphenylarsine (DMCPA) is a chemical compound that has been historically used in chemical warfare. It is an organoarsenic compound, which means it contains carbon-arsenic bonds, and is classified as a vesicant or blister agent, similar to mustard gas. DMCPA is known for its ability to cause severe blistering of the skin and mucous membranes upon exposure. Due to its hazardous nature, its use, production, and stockpiling have been restricted under the Chemical Weapons Convention (CWC).

Chemistry[edit | edit source]

DMCPA, with the chemical formula C_7H_6AsCl_2, is a chlorinated derivative of phenylarsine. It is a colorless, oily liquid at room temperature, with a boiling point of 220°C. DMCPA is poorly soluble in water but soluble in organic solvents such as benzene, ethanol, and diethyl ether.

History[edit | edit source]

The use of chemical weapons, including DMCPA, dates back to World War I, where various chemical agents were deployed to inflict injury or death upon enemy forces. DMCPA was developed during this time as a potential chemical warfare agent. However, its use in conflict has been limited, partly due to the development of more effective or easier-to-handle chemical agents.

Effects on Health[edit | edit source]

Exposure to DMCPA can cause severe chemical burns and blistering of the skin. If inhaled, it can damage the respiratory tract, leading to life-threatening conditions such as pulmonary edema. The eyes are also particularly susceptible to damage from exposure, potentially resulting in blindness. Immediate decontamination and medical treatment are critical for those exposed to DMCPA.

Regulation and Disposal[edit | edit source]

The production and use of DMCPA as a weapon are prohibited under the Chemical Weapons Convention, which was adopted in 1993 and entered into force in 1997. Signatory countries are required to declare and destroy their stockpiles of chemical weapons, including DMCPA, under international supervision. The disposal of DMCPA must be carried out with caution to prevent environmental contamination and exposure to humans.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD