Nitrendipine
(Redirected from Deiten)
Nitrendipine is a calcium channel blocker of the dihydropyridine class. It is used in the treatment of hypertension and angina pectoris.
Mechanism of Action[edit | edit source]
Nitrendipine inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Indications[edit | edit source]
Nitrendipine is indicated for the management of hypertension. It may be used alone or in combination with other antihypertensive agents.
Side Effects[edit | edit source]
Common side effects of Nitrendipine include headache, dizziness, flushing, and nausea. Serious side effects may include low blood pressure, heart failure, and arrhythmias.
Contraindications[edit | edit source]
Nitrendipine is contraindicated in patients with known hypersensitivity to dihydropyridines.
Drug Interactions[edit | edit source]
Nitrendipine may interact with other drugs such as beta blockers, digoxin, cimetidine, and warfarin.
Dosage[edit | edit source]
The usual starting dose of Nitrendipine is 10 mg once daily. The dose may be increased according to the patient's response.
References[edit | edit source]
- Drug Information Handbook. Lexi-Comp, 2007.
| Nitrendipine Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
