Delamanid
Delamanid is an antibacterial medication used for the treatment of tuberculosis. It is specifically used, along with other tuberculosis medications, for active multidrug-resistant tuberculosis. It is taken by mouth.
Medical uses[edit | edit source]
Delamanid is used in combination with other antituberculosis medications to treat adults with multidrug-resistant tuberculosis (MDR-TB) when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.
Side effects[edit | edit source]
Common side effects include nausea, vomiting, and dizziness. Serious side effects may include QT prolongation and a type of irregular heart beat known as torsades de pointes.
Mechanism of action[edit | edit source]
Delamanid is a nitroimidazole antimycobacterial agent. It inhibits the synthesis of mycolic acids, thereby inhibiting the growth of Mycobacterium tuberculosis.
History[edit | edit source]
Delamanid was developed by Otsuka Pharmaceutical and approved for medical use in the European Union in April 2014.
Society and culture[edit | edit source]
As of 2016, delamanid is one of the newer medications used to treat tuberculosis. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
