Deletion mutation

Deletion Mutation is a type of mutation that involves the removal of genetic material. These mutations can occur in a number of ways and can have a variety of effects on the organism.

Overview

A deletion mutation can occur in any size, from a single DNA base pair to a large segment of a chromosome. Deletion mutations can cause diseases such as Cystic fibrosis and Sickle cell anemia.

Causes

Deletion mutations can be caused by errors during DNA replication or meiosis, or by exposure to radiation or chemicals that damage DNA.

Types of Deletion Mutations

There are two main types of deletion mutations: interstitial deletions and terminal deletions.

Interstitial Deletions

Interstitial deletions occur when a segment of a chromosome is lost from the middle. This can result in the loss of several genes.

Terminal Deletions

Terminal deletions occur when a segment of a chromosome is lost from the end. This can result in the loss of one or more genes at the end of the chromosome.

Effects of Deletion Mutations

The effects of deletion mutations can vary widely, depending on the size of the deletion and its location. Some deletion mutations have no noticeable effect, while others can cause serious diseases or conditions.

See Also

• Insertion mutation
• Point mutation
• Frameshift mutation

References

Deletion mutation Resources
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